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  1. In 2 lasting studies, disheartened patients who had replied to citalopram throughout an initial 6 or 8 weeks of acute therapy (set dosages of 20 or 40 mg/day in one research study as well as flexible doses of 20 to 60 mg/day in the second study) were randomized to continuation of citalopram or to inactive medicine. In both studies, individuals receiving continuous citalopram therapy experienced considerably better relapse rates over the subsequent 6 months as compared to those obtaining placebo. In the fixed-dose research study, the reduced price of depression regression was similar in people obtaining 20 or 40 mg/day of citalopram.

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    Evaluations of the relationship between treatment end result and age, race, and gender did not suggest any type of differential cooperation on the basis of these client attributes.


    Very changeable outcomes have been seen in the professional development of all antidepressant medicines. Moreover, in those situations when the drugs have actually not been researched in the very same measured medical trial(s), comparisons among the results of research studies reviewing the performance of different antidepressant drug products are naturally unstable. Since disorders of testing (e. g. person samples, investigators, doses of the therapies administered as well as compared, end result procedures, and so on) differ among trials, it is practically difficult to differentiate a distinction in medicine impact from a distinction as a result of among the confounding factors simply specified.

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